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Posts Tagged ‘cancer’

Early Smokers At Increased Risk of Developing Lung Cancer

Wednesday, May 4th, 2011

According to Boomer Health & Lifestyle, lung cancer risk is higher for those who start smoking early in their life. According to Dr. Otis Brawley, individuals who start smoking at an early age have an increased chance of developing lung cancer later in life. The Chief Medical Officer at the American Cancer Society said that the risk increases particularly in a person’s mid to late 50s and peaks in their late 70s. The number of cigarettes smoked daily and number of years a person spends smoking also add to the risk.

According to the doctor, one third of heavy smokers develop lung cancer. Research has shown that 15 to 20 out of every 100 patients diagnosed with lung cancer have had the bad habit most of their lives. Second hand smoke has lead to some of the diagnosis, while for some the cause is unknown.

Brawley cautions that smoking causes other health issues and not just lung cancer. The bad habit is known to cause 14 different cancers, including those of the head, neck, stomach, kidney, esophagus, pancreas, and bladder. It may also be linked to leukemia, ulcers, high blood pressure, diabetes, bronchitis, emphysema, osteoporosis and reproductive disorders.

A recent study has found that smokers of mentholated cigarettes are no more likely to develop lung cancer than other smokers. In fact, menthol smokers had a lower risk of developing lung cancer, according to a study published in the journal of the National Cancer Institute. The study found that mentholated cigarette smokers were about 12 times more likely to develop lung cancer, while non-menthol smokers had a 21 times the risk of developing the disease.

Genome Sequencing May Be Used As a Cancer Diagnostic Tool

Friday, April 29th, 2011

According to Medical News Today, sequencing a cancer patient’s genome can be an effective diagnostic tool in aiding doctors to find the best treatment. Researchers from Washington University School of Medicine in St. Louis published a study in the journal of the American Medical Association showing that genome sequencing can lead to effective cancer treatment.

In the first study conducted by the group, a 39-year-old female patient with leukemia had her genome sequenced which lead to a change in treatment. The sequencing showed doctors a novel genetic error which doctors used to recommend targeted chemotherapy instead of a cell transplant. The patient is now in remission after successful chemotherapy treatment. The patient’s oncologist said that sequencing the genome offered the doctors an opportunity to make the correct call in recommending further therapy instead of a significantly risky stem cell transplant.

The second study conducted by the same group sequenced the genome of a deceased 42-year old female patient who had developed breast and ovarian cancer. The sequence detected a new mutation in a gene known to considerably raise the risk of cancer. Her family was informed and subsequently advised to receive genetic counseling, which resulted in findings that the patient’s three offspring are at high risk of developing cancer early on in life.

Genome sequencing could make a major difference in the lives of many cancer patients and their families. Both studies showed value in using genome sequencing as a diagnostic tool and perhaps even a cancer prevention method.

Study Finds Lack of Clinical Trials in Top Four Deadliest Cancers

Wednesday, April 27th, 2011

According to Adelaide Now, a recently published study in the Medical Journal of Australia suggests that four of the five cancers that result in the greatest health crisis seriously lack critical trials. The study examined lung, colorectal, prostate and pancreatic cancers.

Rachel Dear, MD and lead researcher of the study said that 386 recent interventional cancer trials in Australia did not include a lot of the major cancers. About 24 were conducted on lung cancer, which is a cancer with the greatest impact of quality of life and life expectancy. Colorectal cancer had 21 trials, even though it is second in terms of life expectancy.

The study found that breast cancer was the most researched type of cancer. The Cancer Council said that clinical research for all types of cancer is necessary in order to find the best way to improve treatment for patients. The council said that lung cancer was the biggest killer and the most easily prevented type of cancer, followed by colorectal cancer. For women, breast cancer is the biggest killer and the third most punishing cancer in terms of healthy life lost.

Some say the study only included registered clinical trials in Australia which did not include unregistered trials. Compulsory registering of trials would allow better research and accurate database in terms of finding out which cancer type research needs further progress. Clinical trials are necessary and are essential in making a difference in survival rates for both men and women.

Biomarkers May Help Detect Metastasis With Melanoma

Monday, April 25th, 2011

According to the Doctors Lounge, a new study has found that biomarkers may predict metastasis in people with melanoma. A set of plasma biomarkers may be useful in predicting which patients are at risk for metastasis, according to a study published in the Clinical Cancer Research.

Harriet M. Kluger, M.D. of the Yale Cancer Center in Connecticut and a team of researchers measured plasma proteins in 108 metastatic melanoma patients and 108 patients with resected stage I or II disease. The group studied protein levels in the former group.

The researchers found seven biomarkers, all which were higher in metastatic melanoma patients than in those with early-stage of the cancer. 81 percent of the early-stage patients had no marker elevation. In 69 percent of those with metastatic disease at least one marker had an elevation.

The team used blood tests to predict the risk of metastasis with melanoma, which would be a much cheaper method than periodic imaging tests used today. According to the Association for Cancer Research, 68,130 Americans were diagnosed with melanoma in 2010, and 8,700 died of the skin cancer. Most deaths from melanoma result from metastasis.

TV broadcaster Kerry Smith died this week from melanoma. She had worked at The Breeze radio station and presented on Radio Pacific and RadioLive, and formerly worked on MediaWorks. The Breeze FM presenter took medical leave in January, saying she wanted to focus on her treatment and recovery from skin cancer. Melanoma is the most dangerous type of skin cancer and leading cause of death from skin disease.