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Archive for the ‘Lung Cancer’ Category

Radon Responsible for Lung Cancer Deaths, Low Survival Rate Found

Friday, May 6th, 2011

According to CBS Atlanta, lung cancer kills thousands of Americans each year. Smoking, radon and secondhand smoke have all been linked to the development of lung cancer. While treatable, the survival rates of lung cancer are one of the lowest. Between 11 and 15 percent of those diagnosed will live beyond five years. However, in many cases lung cancer is preventable.

The EPA estimates that 20,000 lung cancer deaths each year are radon-related. Radon is a form of ionizing radiation and is a proven carcinogen. Approximately 85% of radon-induced lung cancer patients die within 4-5 years of diagnosis.

Two studies have shown definite evidence of association between residential radon exposure and lung cancer. One study in North America combined data from several previous residential studies. Both studies confirmed the radon health risks predicted by occupational studies of underground miners who breathed radon for several years. Some researchers had questioned earlier whether occupational studies could be used to calculate risks from exposure to exposure to radon in the home environment.

The EPA’s former director of Indoor Environment Division said that the studies’ findings effectively end doubt about the risks of having radon in the home. Breathing even low levels of radon could lead to lung cancer, said Tom Kelly.

Dr. Michael Repacholi, coordinator of WHO’s Radiation and Environmental Health Unit said that radon poses a health risk to populations all over the world, but that the risk can be reduced. While radon health risks have received widespread attention, the carcinogen is the main source of exposure to ionizing radiation, and accounts to 50% of the public’s exposure to naturally-occurring sources of radiation, said Repacholi.

Early Smokers At Increased Risk of Developing Lung Cancer

Wednesday, May 4th, 2011

According to Boomer Health & Lifestyle, lung cancer risk is higher for those who start smoking early in their life. According to Dr. Otis Brawley, individuals who start smoking at an early age have an increased chance of developing lung cancer later in life. The Chief Medical Officer at the American Cancer Society said that the risk increases particularly in a person’s mid to late 50s and peaks in their late 70s. The number of cigarettes smoked daily and number of years a person spends smoking also add to the risk.

According to the doctor, one third of heavy smokers develop lung cancer. Research has shown that 15 to 20 out of every 100 patients diagnosed with lung cancer have had the bad habit most of their lives. Second hand smoke has lead to some of the diagnosis, while for some the cause is unknown.

Brawley cautions that smoking causes other health issues and not just lung cancer. The bad habit is known to cause 14 different cancers, including those of the head, neck, stomach, kidney, esophagus, pancreas, and bladder. It may also be linked to leukemia, ulcers, high blood pressure, diabetes, bronchitis, emphysema, osteoporosis and reproductive disorders.

A recent study has found that smokers of mentholated cigarettes are no more likely to develop lung cancer than other smokers. In fact, menthol smokers had a lower risk of developing lung cancer, according to a study published in the journal of the National Cancer Institute. The study found that mentholated cigarette smokers were about 12 times more likely to develop lung cancer, while non-menthol smokers had a 21 times the risk of developing the disease.

Genome Sequencing May Be Used As a Cancer Diagnostic Tool

Friday, April 29th, 2011

According to Medical News Today, sequencing a cancer patient’s genome can be an effective diagnostic tool in aiding doctors to find the best treatment. Researchers from Washington University School of Medicine in St. Louis published a study in the journal of the American Medical Association showing that genome sequencing can lead to effective cancer treatment.

In the first study conducted by the group, a 39-year-old female patient with leukemia had her genome sequenced which lead to a change in treatment. The sequencing showed doctors a novel genetic error which doctors used to recommend targeted chemotherapy instead of a cell transplant. The patient is now in remission after successful chemotherapy treatment. The patient’s oncologist said that sequencing the genome offered the doctors an opportunity to make the correct call in recommending further therapy instead of a significantly risky stem cell transplant.

The second study conducted by the same group sequenced the genome of a deceased 42-year old female patient who had developed breast and ovarian cancer. The sequence detected a new mutation in a gene known to considerably raise the risk of cancer. Her family was informed and subsequently advised to receive genetic counseling, which resulted in findings that the patient’s three offspring are at high risk of developing cancer early on in life.

Genome sequencing could make a major difference in the lives of many cancer patients and their families. Both studies showed value in using genome sequencing as a diagnostic tool and perhaps even a cancer prevention method.

Study Finds Lack of Clinical Trials in Top Four Deadliest Cancers

Wednesday, April 27th, 2011

According to Adelaide Now, a recently published study in the Medical Journal of Australia suggests that four of the five cancers that result in the greatest health crisis seriously lack critical trials. The study examined lung, colorectal, prostate and pancreatic cancers.

Rachel Dear, MD and lead researcher of the study said that 386 recent interventional cancer trials in Australia did not include a lot of the major cancers. About 24 were conducted on lung cancer, which is a cancer with the greatest impact of quality of life and life expectancy. Colorectal cancer had 21 trials, even though it is second in terms of life expectancy.

The study found that breast cancer was the most researched type of cancer. The Cancer Council said that clinical research for all types of cancer is necessary in order to find the best way to improve treatment for patients. The council said that lung cancer was the biggest killer and the most easily prevented type of cancer, followed by colorectal cancer. For women, breast cancer is the biggest killer and the third most punishing cancer in terms of healthy life lost.

Some say the study only included registered clinical trials in Australia which did not include unregistered trials. Compulsory registering of trials would allow better research and accurate database in terms of finding out which cancer type research needs further progress. Clinical trials are necessary and are essential in making a difference in survival rates for both men and women.