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Archive for June, 2009

Phase II clinical trial offers hope to mesothelioma victims

Wednesday, June 24th, 2009
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The Italian biotechnology company MolMed has announced positive results for their Phase II trial of NGR-hTNF for the treatment of malignant pleural mesothelioma.

The trial, which consisted of 57 malignant pleural mesothelioma patients that were previously treated with chemotherapy, found NGR-hTNF useful as both a theraputic option and as part of a combination therapy with most chemotherapy methods.

During the trial, one group of patients received the drug every three weeks and the other received it each week. Both groups received low doses of the drug intravenously. The results of the trial showed a median overall survival rate of one year. The disease control rate during the trial was 46 percent, which was maintained for a median total duration of 4.7 months.

MolMed plans to start another Phase II trial of NGR-hTNF in combination with cisplatin for lung cancer. Cisplatin, a chemotherapy drug that is often combined with newer medications ton increase the effectiveness of treatment, is one of the most effective treatment options available for pleural mesothelioma when combined with another chemotherapy drug called Alimta.

Mesothelioma is a form of cancer that is linked to asbestos exposure. Workplace exposure to asbestos in places like aluminum smelters, oil refineries, shipyards and the construction industry puts workers at risk of developing asbestos-related diseases like asbestosis, lung cancer, gastrointestinal cancer and mesothelioma.

Cancer signs that are often ignored

Monday, June 22nd, 2009

Lethal Weapon 3 rip When cancer manifests in your body, it sends off subtle signals of its presence. Here is a list of some symptoms that often go unnoticed.

*Changes in nipples or breasts on one side — This may be an early sign of breast cancer. Look for unexplained redness, swelling, discharges, dimples, lumps or rough spots as well as inverted or turned nipples.

*Unusual bleeding — This could be a warning for cervical, uterine, or colorectal cancer. Watch out for unusual pain or unpleasant odors, bleeding after intercourse, blood in urine, blood in stool, or periods that are unexpected, unusually heavy, and painful.

*Change in bowel or bladder — Continual constipation, diarrhea, stomach aches, increase in urination, pain while urinating, or pain while having a bowel movement could be related to colon, bladder, or kidney cancer.

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*Abdominal/pelvic pain or bloating — Sudden or continual bloating (that is unrelated to menstrual cycle), pain or abdominal sensitivity, always feeling full or being unable to eat may be signs of ovarian cancer.

*Sudden weakness or weight loss/gain — If you find yourself feeling inexplicably weak, or gaining/losing weight without having made changes in your diet, it is possible you are experiencing the early signs of colon cancer or cancer of another digestive system.

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*Sore throat, cough, or hoarseness — These could be symptoms of lung cancer, leukemia, or throat cancer if they are not due to a cold. May also include chest pain or earaches.

*Difficulty breathing — Wheezing, shortness of breath, or other difficulty breathing that is not due to a cold, allergies, or asthma may mean early stage lung cancer.

*Problems with digestion — Difficulty swallowing, frequent indigestion, or blood in vomit are serious conditions that could be linked to esophageal, throat, or lung cancer.

*Swollen lymph nodes — Certain types of blood and lymphatic cancers cause lumps in the neck, under the arm, or in the groin.

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*Changes in a wart, mole, or skin spots — Skin cancer can cause preexisting skin conditions to change. If you notice unusual changes in size, color, shape, or border, tell your doctor.

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*Sores that won’t heal, excessive bruising or bleeding — These could indicate many things. This includes sores in and around the mouth, throat, skin lesions and genital sores.

Early identification of cancer increases your chances of survival. Be aware of your body, and be careful not to ignore these unexplained symptoms that might indicate cancer.

Asbestos exposure at General Motors

Monday, June 22nd, 2009

A former worker at the General Motors production plant in Michigan may have contracted mesothelioma lung cancer due to years of asbestos exposure.

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The Memory Keeper’s Daughter dvdrip Though the man retired from GM almost 20 years ago, his daughter strongly believes that his recent diagnoses of lung, brain, and bladder cancer are tied to the asbestos fibers in the pipes and boilers at the plant. It is likely that the man has in fact contracted mesothelioma after too many long days working in the foundry and assembling units for the car company.

To strengthen their case, the plant where he worked at was torn down because it was laden with asbestos. The plant was situated in the middle of town—during demolition, asbestos fibers could have gotten into the air. Several other former employees of the Michigan plant have been diagnosed with asbestos related illnesses.

Lockjaw: Rise of the Kulev Serpent trailer Right now, people who have asbestos-injury claims against GM are fighting against the government-supported plan to sell the company. Since the company owes them money, these people hold a stake in GM and have so far been left out of negotiations. Sale of GM could be unconstitutional if these claimants remain unrepresented.

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